David Ruiz-Carrillo


Qualifications

Ph.D.   Martin-Luther Halle-Wittenberg University,  Germany,  Biochemistry,  2009

BSc   University Complutense of Madrid,  Spain, Madrid,  Biochemistry,  2001


Experience

Lecturer, Xi'an Jiaotong-Liverpool University (2013 - Present), Suzhou, China-PRC.

Postdoc in structural biology, The group of Assoc. Prof. J. Lescar, Nanyang Technological University (2011 - 2013), Singapore, Singapore.

Postdoc in structural biology, The group of Prof. M. T. Stubbs, Martin-Luther Halle-Wittenberg University (2009 - 2011), Halle/S, Germany.

Research associate, Probiodrug AG CSO Prof H. U. Demuth (2002 - 2009), Halle/S, Germany.


Publications 

Huang, Q., Li, Q., Joy, J., Chen, A., Carrillo, D. R., Hill, J., Lescar, J., & Kang, C. (2013).  Lyso-myristoyl phosphatidylcholine micelles sustain the activity of Dengue non-structural (NS) protein 3 protease domain fused with the full-length NS2B.   Protein Expr Purif, 92 (2), 156-62.


Koch, B., Kolenko, P., Buchholz, M., Carrillo, D. R., Parthier, C., Wermann M, Rahfeld JU, Reuter G, Schilling S, Stubbs MT, Demuth HU. (2012).  Crystal Structures of Glutaminyl Cyclases from Drosophila melanogaster Reveal Active Site Conservation between Insect and Mammalian QCs.   Biochemistry, 51 (37), 7383-92.


Carrillo, D. R., Chandrasekaran, R., Nilsson, M., Cornvik, T., Liew, C. W., S. M. Tan and J. Lescar (2012).  Lescar Structure of the human Rack1 protein at 2.45Å resolution.   Acta Cryst, 867-872.


Carrillo, D. R., Koch, B., Parthier, C., Wermann, M., Dambe, T., Buchholz M, Ludwig HH, Heiser U, Rahfeld JU, Stubbs MT, Schilling S, Demuth HU. (2011).  Structures of glycosylated mammalian glutaminyl cyclases reveal conformational variability near the active center.   Biochemistry, 50 (28), 6280-8.


Carrillo, D. R., Parthier, C., Jänckel, N., Grandke, J., Stelter, M., Schilling S, Boehme M, Neumann P, Wolf R, Demuth HU, Stubbs MT, Rahfeld JU. (2010).  Kinetic and structural characterization of bacterial glutaminyl cyclases from Zymomonas mobilis and Myxococcus xanthus.   Biol Chem, 391 (12), 1419-28.


Schulz, I., Zeitschel, U., Rudolph, ., Carrillo, D. R., Rahfeld, J., Gerhartz B, Bigl V, Demuth HU, Rossner S. (2005).  Subcellular localization suggests novel functions for prolyl endopeptidase in protein secretion.   J Neurochem, 94 (4), 970-9.